Gianotti-Crosti syndrome is a skin rash especially in children, triggered by a viral or more seldom by a bacterial infection. The symmetrical rash evolves rapidly. Reddish papules are seen on the skin in clusters or coalesced to form elevated patches. Besides cheeks, rash is also found in the extremities, especially at the elbows and knees but only on the extensor side. The skin is intact. There is no significant itching and the child is in good general condition. The rash will resolve spontaneously in a few weeks. Hepatitis B is often the triggering factor in countries where this infection is more common. See also a close-up picture .