Pyoderma in the skin of the hand. Pustular infection can be caused by Staphylococcus aureus, but in more severe cases pyogenic streptococci are (also) often found. Oral cephalosporins are usually curative, but bacterial culture with an antibiotic sensitivity test should be carried out. The infection is more common in skin with dermatitis. To prevent recurrent infection, this should be treated as well.