Fungal infection in the hands. Fine scaling is seen in the palm and fingers of the left hand; the right hand is symptomless. Itching is only slight. In most cases only one hand is affected ("one hand – two feet syndrome"). In the palm, there is no pronounced rim at the border of the affected area: this makes the border rather indistinguishable, with the scaling as the main difference. Oral antifungals are needed for permanent cure. The nails are also often affected which determines the duration of the therapy. Fungal infection in the hands is uncommon.